For retail shopping, residents here head west to Lancaster or, for a wider variety, to Cheektowaga. Both are a short drive west. Eastern Hills Mall, to the northwest in Williamsville, also is nearby. For grocery shopping, neighboring Alden has a Topps Friendly Markets store on Broadway Avenue. The closest Wegmans stores are in nearby Depew, on Transit Road (Route 78) and on Dick Road.
Students who live in Marilla attend either the Iroquois Central School District or the Alden Central School District. The closest hospitals are both about 14 miles away: Sisters of Charity-St. Joseph Campus in Cheektowaga and Mercy Hospital in Orchard Park. The Marilla Free Library is at the intersection of Bullis Road and Two Rod Road (Route 358).